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ISSN: 2639-9431

Precision Nanomedicine

CLINAM-ISNM's free, open-access, peer-reviewed journal

Research Article
April 01, 2025 EDT
Diagnosis of Alzheimer’s Disease, Parkinson’s Disease, Frontotemporal Dementia, and Paranoid Schizophrenia via Complex Network Analysis of EEG Data
Miguel Angel Vargas Cruz
We present a novel diagnostic method utilizing complex network analysis utilizing electroencephalogram data and achieving exceptional classification accuracy across a range of mental disorders.

Recent blog posts

UCD is recruiting!
UCD is recruiting!
The University College Dublin is looking for candidates for a Lecturer / Assistant Professor position
49 Precision Nanomedicine Board members are on the World's top 2% scientists list - the 2024 update
49 Precision Nanomedicine Board members are on the World’s top 2% scientists list - the 2024 update
Forty-nine active Board members of PRNANO are in the World’s Top 2% of scientists, and 30 of them are in the top 1%, demonstrating the quality of our journal.
The NCL's Assay Cascade Protocols are now on the National Library of Medicine's Bookshelf!
The NCL’s Assay Cascade Protocols are now on the National Library of Medicine’s Bookshelf!
We are happy to share that the NCL's assay cascade protocols, an incredible asset for nanomedicine researchers, are now publicly available. You are encouraged to use and cite them!
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Review
March 12, 2025 EDT
Safe Bloodstream Concentration Limits for Microscale Nanorobots
Robert Freitas

This article surveys experimental studies on the pathological effects of intravenous injection of micro-particles of various sizes and compositions looking for the applicability of microscale diamondoid nano-robots in the bloodstream.

Review
March 04, 2025 EDT
Nanotechnology-Powered Cosmetics: Progress in Hyperpigmentation Treatment
Maha N. Abu HajlehHamdi NsairatSama Al KazazAli Al-SamydaiHind RasheedAlia K. Ibrahim

This study thoroughly explores how different nanomaterials can improve cosmetic formulations for treating hyperpigmentation.

In vitro study of size-dependent inhibition of human cytochrome P450 (P450) P450-1A2, P450-2A6, P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5 by zinc oxide nanoparticles (ZnONPs) Research Article
February 01, 2025 EDT
In vitro study of size-dependent inhibition of human cytochrome P450 (P450) P450-1A2, P450-2A6, P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5 by zinc oxide nanoparticles (ZnONPs)
Lamia ChowdhuryYuh Fen PungSwee Yong PungChin Eng OngCin KongYan Pan

This study demonstrates that smaller ZnO nanoparticles exhibit stronger inhibitory effects on key P450- enzymes (P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5) compared to larger particles.

Paranoid Schizophrenia Diagnosis via Complex Network Analysis on EEG Data Research Article
January 21, 2025 EDT
Paranoid Schizophrenia Diagnosis via Complex Network Analysis on EEG Data
Miguel Angel Vargas Cruz

This study presents a novel approach leveraging complex network analysis and Discrete Fourier Transform (DFT) applied to electroencephalogram (EEG) data for diagnosing schizophrenia with a classification accuracy of 93%.

Synthesis and Characterization of 5-Fluoroacil Loaded Calcium Carbonate Nanoparticles for Targeted Cancer Therapy Research Article
December 22, 2024 EDT
Synthesis and Characterization of 5-Fluoroacil Loaded Calcium Carbonate Nanoparticles for Targeted Cancer Therapy
Kshidan Marim Abdullah SalemMohamed Ahmed IbrahimKim Wei ChanMd Zuki Abu BakarNoorjahan Banu AlitheenMohammed AlsubbiAhmad Faizal Abdull RazisNorsharina Ismail

This study synthesized 5-Fluorouracil-loaded calcium carbonate nanoparticles using the co-precipitation method. The 5-FU-CaCO3 NPs showed reduced systemic toxicity and enhanced therapeutic efficacy in vitro.

Review
December 11, 2024 EDT
Nanotechnology-Enhanced Controlled Release Systems in Topical Therapeutics
Yohannes Teklehaimanot

This review examines recent advances, challenges, and prospects of controlled-release nanoparticles for topical drug delivery with improved therapeutic outcomes and patient care. A summary table is in the supporting file.

Research Article
October 31, 2024 EDT
Self-assembled Human Serum Protein-based Core-shell Nanoparticles to inhibit key oncogenic signalling in Drug-Resistant Leukemia
Archana Payickattu RetnakumaryLekshmi G KumarNeeraj SidharthanPavithran KeechilatGiridharan L. MalarvizhiPrasanna L HanumanthuMadhavan V ThampiDeepthy MenonKrishnakumar MenonShantikumar V NairManzoor Koyakutty

This study introduces two unique core-shell nanoparticle (CS-NP) systems crafted from natural proteins, simultaneously targeting two crucial oncogenic pathways in refractory chronic myeloid leukemia.

In vitro characterization of beta-cyclodextrin liposomal formulation of cisplatin nanomedicine Research Article
October 01, 2024 EDT
In vitro characterization of beta-cyclodextrin liposomal formulation of cisplatin nanomedicine
Panijapatr Wasubhadtanasaka

Combining cisplatin with PARP inhibitors induces mitochondrial permeabilization and activates the intrinsic apoptosis pathway, which in turn, increases cytotoxicity. Reducing the required dosage promises an advance in cancer therapy.

A shortage of funding or not enough healthcare projects? Editorial
September 26, 2024 EDT
A shortage of funding or not enough healthcare projects?
Mike Eaton

This note is written in the hope that it will improve the success of small and medium-sized enterprises in their attempts to get non-academic investment funding for development.

Advancements in Lipid Nanoparticle Technologies for Precision Targeting in Therapeutic Delivery Review
July 22, 2024 EDT
Advancements in Lipid Nanoparticle Technologies for Precision Targeting in Therapeutic Delivery
Peiyang Gao

This review highlights strategies that improve the targeting of LNPs by employing various methods to enhance therapeutic outcomes by ensuring drugs reach specific cells or tissues with high accuracy.

A Beginner's Guide to Writing Scientific Manuscripts Editorial
June 30, 2024 EDT
A Beginner’s Guide to Writing Scientific Manuscripts
Lajos Balogh

A practical guide for less experienced writers by describing the procedure the author uses to write scientific articles.